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Search Results for " bipolar disorder "

17

Compounds

Cat No. Product Name Synonyms Targets
T11722 JNJ-37822681 dihydrochloride Dopamine Receptor
JNJ-37822681 has potential for the treatment of schizophrenia and bipolar disorder.JNJ-37822681 dihydrochloride is a potent, specific, centrally active, fast-dissociating dopamine D2 receptor antagonist with a moderate b...
T1602 Valproic acid sodium salt Sodium Valproate Mitophagy , Gamma-secretase , HIV Protease , GABA Receptor , HDAC , Autophagy
Valproic acid sodium salt (Sodium Valproate) is the sodium salt form of valproic acid with anti-epileptic activity. Valproic acid sodium salt is converted into its active form, valproate ion, in blood. Although the mecha...
T7064 Valproic Acid Sodium valproate,2-Propylpentanoic Acid,VPA,Depakine,2-Propylvaleric Acid Mitophagy , Gamma-secretase , HIV Protease , GABA Receptor , Sodium Channel , HDAC , Autophagy
Valproic Acid (2-Propylpentanoic Acid) is an HDAC inhibitor that inhibits HDAC1 activity, induces HDAC2 degradation, and is orally active. Valproic Acid can be used in epilepsy and bipolar disorder research.
T6474 Divalproex Sodium Valproate semisodium,Epival HDAC
Divalproex Sodium (Valproate semisodium) binds to and inhibits gamma-aminobutyric acid (GABA) transaminase and its anticonvulsant activity may be exerted by increasing brain concentration of GABA and by inhibiting enzyme...
T2342 Raxatrigine CNV1014802,CNV 1014802,GSK-1014802,CNV-1014802 Sodium Channel
Raxatrigine (CNV 1014802) has been investigated for the treatment of Bipolar Disorder and Bipolar Depression.
T28809 SLV-310 SLV 310,SLV310 Dopamine Receptor , 5-HT Receptor
SLV-310 is a potent dopamine D2 receptor antagonist and 5-HT reuptake receptor inhibitor used in the study of neurological disorders such as bipolar disorder and schizophrenia.
T32633 Lensiprazine SLV314,SLV-314,SLV 314 Dopamine Receptor , 5-HT Receptor
Lensiprazine (SLV314) is a potent dopamine D(2) receptor antagonist that acts as a serotonin reuptake inhibitor , and can be used to study bipolar disorder and schizophrenia.
T1951 Asenapine Maleate Org 5222 maleate,Org 5222 5-HT Receptor
Asenapine Maleate (Org 5222 maleate) is a second generation (atypical) antipsychotic agent that is taken sublingually and used in the treatment of schizophrenia and manic or mixed episodes associated with bipolar 1 disor...
T1735 Lurasidone hydrochloride Lurasidone HCl,SM-13496 (Hydrochloride),SM-13496 Dopamine Receptor , 5-HT Receptor , Norepinephrine
Lurasidone hydrochloride (Lurasidone HCl) is a thiazole derivative and atypical antipsychotic agent that functions as a dopamine D2 receptor antagonist; serotonin 5-HT2 receptor antagonist, serotonin 5-HT7 receptor antag...
T0162 Quetiapine ICI204636,Quetiapin Dopamine Receptor , 5-HT Receptor , Adrenergic Receptor , AChR , Histamine Receptor
Quetiapine (ICI204636) is used for the therapy of schizophrenia, and for the treatment of acute manic episodes associated with bipolar I disorder. The mechanism of quetiapine' action is thought by mediated through antago...
T22589 Asenapine hydrochloride Others
Asenapine is a new atypical antipsychotic developed for the treatment of schizophrenia and acute mania associated with bipolar disorder.
T30131 Aripiprazole cavoxil
Aripiprazole cavoxil is used in Treatment of Schizophrenia, Bipolar Disorder, and Clinical Depression.
T70964 Olanzapine/Samidorphan
Olanzapine/Samidorphan is a combination of olanzapine and the opioid receptor antagonist samidorphan is under development for the treatment of schizophrenia and bipolar I disorder. The single-tablet combination treatment...
T68706 Olanzapine HCl
Olanzapine HCl is an atypical antipsychotic. It is approved by the U.S. Food and Drug Administration (FDA) for the treatment of schizophrenia and bipolar disorder. Olanzapine is structurally similar to clozapine and quet...
T61804 GSK-3β inhibitor 6
GSK-3β inhibitor 6 is a highly potent inhibitor of GSK-3β, with an IC50 value of 24.4 μM. It demonstrates significant enhancement of hepatocyte glucose uptake (38%). This compound holds great potential for studying vario...
T63129 Asenapine citrate
Asenapine citrate is an atypical antipsychotic drug and is a 5-hydroxytryptamine receptor (pKi: 8.4-10.5), adrenoceptor (pKi: 8.9-9.5), dopamine receptor (pKi: 8.9-9.4), and histamine receptor (pKi: 8.2-9.0) antagonists ...
T63866 GSK-3β inhibitor 7
GSK-3β inhibitor 7 is a GSK-3β inhibitor (IC50: 5.25 μM). GSK-3β inhibitor 7 acts by inserting into the ATP-binding binding pocket of GSK-3β and forming hydrogen bonds. GSK-3β inhibitor 7 has a high rate of glucose uptak...
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